Sequence Detail

ID/Version

Q9Z0R4 F8VQE5 Q9R143 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Intersectin-1 {ECO:0000305};AltName: Full=EH and SH3 domains protein 1 {ECO:0000303|PubMed:10064583};

Provider

SWISS-PROT

Sequence

Polypeptide 1714 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Itsn1	intersectin 1 (SH3 domain protein 1A)	57	108	3	56

Sequence references in MGI

J:53505 Sengar AS, et al., The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15. EMBO J. 1999 Mar 1;18(5):1159-71
J:74670 Jenna S, et al., The Activity of the GTPase-activating Protein CdGAP Is Regulated by the Endocytic Protein Intersectin. J Biol Chem. 2002 Feb 22;277(8):6366-73
J:140030 Yu Y, et al., Mice deficient for the chromosome 21 ortholog Itsn1 exhibit vesicle-trafficking abnormalities. Hum Mol Genet. 2008 Nov 1;17(21):3281-90
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:184122 Henne WM, et al., FCHo proteins are nucleators of clathrin-mediated endocytosis. Science. 2010 Jun 4;328(5983):1281-4
J:197322 Sakaba T, et al., Fast neurotransmitter release regulated by the endocytic scaffold intersectin. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8266-71
J:231224 Rossi P, et al., A Novel Topology of Proline-rich Transmembrane Protein 2 (PRRT2): HINTS FOR AN INTRACELLULAR FUNCTION AT THE SYNAPSE. J Biol Chem. 2016 Mar 18;291(12):6111-23
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89