Sequence Detail

ID/Version

Q9Z0Y7 Q8BRB9 A2BHF6 (UniProt | EBI)

Last sequence update: 2008-01-15
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Insulin receptor substrate 4; Short=IRS-4;AltName: Full=Phosphoprotein of 160 kDa; Short=pp160;

Provider

SWISS-PROT

Sequence

Polypeptide 1216 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irs4	insulin receptor substrate 4	9	112	2	7

Sequence references in MGI

J:53778 Fantin VR, et al., Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene. Endocrinology. 1999 Mar;140(3):1329-37
J:59964 Fantin VR, et al., Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. Am J Physiol Endocrinol Metab. 2000 Jan;278(1):E127-33
J:77039 Krebs DL, et al., SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. Mol Cell Biol. 2002 Jul;22(13):4567-78
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563