Sequence Detail

ID/Version

Q9Z1N6 Q91ZX9 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Secreted frizzled-related sequence protein 4; Short=FRP-4; Short=sFRP-4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 351 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sfrp4	secreted frizzled-related protein 4	52	114	2	16

Sequence references in MGI

J:39275 Rattner A, et al., A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2859-63
J:49904 Leimeister C, et al., Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev. 1998 Jul;75(1-2):29-42
J:62989 Chang JT, et al., Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium. Hum Mol Genet. 1999 Apr;8(4):575-83
J:71192 Yam JW, et al., Transcriptional activity of the promoter region of rat frizzled-related protein gene. Biochem Biophys Res Commun. 2001 Aug 10;286(1):94-100
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:234467 Simsek Kiper PO, et al., Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease. N Engl J Med. 2016 Jun 30;374(26):2553-62