ID/Version |
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Sequence description from provider |
RecName: Full=GRB2-associated-binding protein 2;AltName: Full=GRB2-associated binder 2;AltName: Full=Growth factor receptor bound protein 2-associated protein 2;AltName: Full=PH domain-containing adaptor molecule p97; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
665
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:51807
Gu H, et al., Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation. Mol Cell. 1998 Dec;2(6):729-40
J:53418 Nishida K, et al., Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. Blood. 1999 Mar 15;93(6):1809-16 J:70424 Gu H, et al., Essential role for Gab2 in the allergic response. Nature. 2001 Jul 12;412(6843):186-90 J:97515 Wada T, et al., The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis. Nat Med. 2005 Apr;11(4):394-9 J:129191 Yu M, et al., Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI. J Immunol. 2006 Feb 15;176(4):2421-9 J:145408 Zhang Y, et al., Abnormal hematopoiesis in Gab2 mutant mice. Blood. 2007 Jul 1;110(1):116-24 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:334006 Choi HK, et al., Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis. Cell Res. 2013 Apr;23(4):524-36 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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