Sequence Detail

ID/Version

Q9Z2G0 Q3V148 Q3ULQ3 Q99NC9 Q3TV57 Q80U13 Q9QZL3 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein fem-1 homolog B {ECO:0000305}; Short=FEM1b {ECO:0000303|PubMed:9828124};AltName: Full=FEM1-beta;AltName: Full=Fem-1-like death receptor-binding protein alpha {ECO:0000303|PubMed:10542291};AltName: Full=Fem-1-like in apoptotic

Provider

SWISS-PROT

Sequence

Polypeptide 627 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fem1b	fem 1 homolog b	39	101	3	21

Sequence references in MGI

J:51387 Ventura-Holman T, et al., The murine fem1 gene family: homologs of the Caenorhabditis elegans sex- determination protein FEM-1. Genomics. 1998 Dec 1;54(2):221-30
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100017 Lu D, et al., Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the fem1b gene. Mol Cell Biol. 2005 Aug;25(15):6570-7
J:139640 Wang X, et al., Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Dev Dyn. 2008 Sep 24;237(10):2963-2972
J:176478 Shi YQ, et al., Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37. Gene. 2011 Oct 10;485(2):153-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296897 Manford AG, et al., A Cellular Mechanism to Detect and Alleviate Reductive Stress. Cell. 2020 Oct 1;183(1):46-61.e21
J:338230 Manford AG, et al., Structural basis and regulation of the reductive stress response. Cell. 2021 Oct 14;184(21):5375-5390.e16