Sequence Detail

ID/Version

Q9Z2R6 (UniProt | EBI)

Last sequence update: 1999-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Protein unc-119 homolog A;AltName: Full=Retinal protein 4; Short=mRG4;

Provider

SWISS-PROT

Sequence

Polypeptide 240 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Unc119	unc-119 lipid binding chaperone	36	99	4	6

Sequence references in MGI

J:49983 Swanson DA, et al., Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptors. Invest Ophthalmol Vis Sci. 1998 Oct;39(11):2085-94
J:123195 Ishiba Y, et al., Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function. Exp Eye Res. 2007 Mar;84(3):473-85
J:136903 Haeseleer F, Interaction and colocalization of CaBP4 and Unc119 (MRG4) in photoreceptors. Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2366-75
J:174011 Zhang H, et al., UNC119 is required for G protein trafficking in sensory neurons. Nat Neurosci. 2011;14(7):874-80
J:207818 Karim Z, et al., UNC119 inhibits dynamin and dynamin-dependent endocytic processes. Cell Signal. 2010 Jan;22(1):128-37
J:282598 Chaya T, et al., Cul3-Klhl18 ubiquitin ligase modulates rod transducin translocation during light-dark adaptation. EMBO J. 2019 Dec 2;38(23):e101409
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89