Sequence Detail

ID/Version

Q9Z2U4 B1AY67 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=ETS-related transcription factor Elf-4;AltName: Full=E74-like factor 4;AltName: Full=Myeloid Elf-1-like factor;

Provider

SWISS-PROT

Sequence

Polypeptide 655 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Elf4	E74 like ETS transcription factor 4	27	105	3	17

Sequence references in MGI

J:79568 Lacorazza HD, et al., The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer and NK-T Cells. Immunity. 2002 Oct;17(4):437
J:149555 Yamada T, et al., Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2. Nat Immunol. 2009 Jun;10(6):618-26
J:149898 Sashida G, et al., ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation. Mol Cell Biol. 2009 Jul;29(13):3687-99
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:321292 Tyler PM, et al., Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation. Nat Immunol. 2021 Jul 29;
J:328935 Sun G, et al., Loss of Function Mutation in ELF4 Causes Autoinflammatory and Immunodeficiency Disease in Human. J Clin Immunol. 2022 May;42(4):798-810