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MRL/Mp-Faslpr Strain Detail
Summary
  • Strain Name
    MRL/Mp-Faslpr
  • Attributes
    mutant strain, spontaneous mutation
  • MGI ID
    MGI:2160471
  • Synonyms
    MRL/Mp-lpr, MRL/Mp-Tnfrsf6lpr
  • Other IDs
    JAX:001420
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Faslpr Fas
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
autoimmune lymphoproliferative syndrome √
Sjogren's syndrome √
systemic lupus erythematosus √
Key √ disease model expected model not found
References
  • Earliest
    J:1159 Mitsuda T, et al., The murine Sm-D autoantigen: multiple genes, genetic polymorphism, evolutionary conservation and lack of intervening sequences in the coding region. J Autoimmun. 1992 Jun;5(3):277-87
  • All
    2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory