B6.Cg-Pmp22<Tr-J> Krt25<Re>/+ +/J Strain Detail MGI Mouse MGI:2161321

B6.Cg-Pmp22^Tr-J Krt25^Re/+ +/J Strain Detail

Summary

2 associated mutations

Mutation Carried	Marker
Krt25^Re	Krt25
Pmp22^Tr-J	Pmp22

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
Charcot-Marie-Tooth disease type 1A	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:000568	JAX	B6.Cg-Pmp22^Tr-J Krt25^Re/+ +/J	exact match to ID

Earliest

J:7222 Henry EW, et al., Comparison of Trembler and Trembler-J mouse phenotypes: varying severity of peripheral hypomyelination. J Neuropathol Exp Neurol. 1983 Nov;42(6):688-706
All

3

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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