B6.129P2-Cftr<tm1Unc>/J Strain Detail MGI Mouse MGI:2163739

B6.129P2-Cftr^tm1Unc/J Strain Detail

Summary

1 associated mutation

Mutation Carried	Marker
Cftr^tm1Unc	Cftr

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
cystic fibrosis	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:002196	JAX	B6.129P2-Cftr^tm1Unc/J	exact match to ID

Earliest

J:2356 Koller BH, et al., Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10730-4
All

9

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24