129P2/OlaHsd-Prnp<tm1Edin>/EdinH Strain Detail MGI Mouse MGI:2177453

129P2/OlaHsd-Prnp^tm1Edin/EdinH Strain Detail

Summary

Strain Name

129P2/OlaHsd-Prnp^tm1Edin/EdinH
Attributes

coisogenic, mutant strain, targeted mutation
MGI ID

MGI:2177453
Synonyms

101LL, 129P2/OlaHsd-Prnp^tm1Edin/2, 129P2/OlaHsd-Prnp^tm1Edin/Edin, 129P2/OlaHsd-Prnp^tm1Edin/H, STOCK Prnp^tm1Edin

1 associated mutation

Mutation Carried	Marker
Prnp^tm1Edin	Prnp

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
Creutzfeldt-Jakob disease
fatal familial insomnia
Gerstmann-Straussler-Scheinker syndrome

Key

√

disease model

expected model not found

2 associated strain records at IMSR

IMSR	Repository	IMSR Strain	Why Matched
EM:11450	EMMA	129P2/OlaHsd-Prnp^tm1Edin/H	exact match to ID
HAR:9181	HAR	129P2/OlaHsd-Prnp^tm1Edin/H	exact match to synonym

Earliest

J:29021 Moore RC, et al., Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations. Biotechnology. 1995 SEP;13(9):999-1004
All

3

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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