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NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ Strain Detail
Summary
  • Strain Name
    NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ
  • Attributes
    congenic, deletion, mutant strain, targeted mutation
  • MGI ID
    MGI:2683535
  • Synonyms
    NOD.129S2(B6)-Casp1tm1Sesh/LtJ
Associated
Mutations,
Markers,
and QTL
2 associated mutations
Mutation Carried Marker
Casp1tm1Sesh Casp1
Casp4del Casp4
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
type 1 diabetes mellitus √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
JAX:004947 JAX NOD.129S2(B6)-Casp1tm1Sesh Casp4del/LtJ exact match to ID
References
  • Earliest
    J:22964 Li P, et al., Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell. 1995 Feb 10;80(3):401-11
  • All
    10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory