About   Help   FAQ
B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax Strain Detail
Summary
  • Strain Name
    B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax
  • Attributes
    congenic, mutant strain, transgenic
  • MGI ID
    MGI:3619245
  • Synonyms
    APPswe line C3-3 x PS1dE9 line S-9, B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/J
  • Other IDs
    JAX:005866, MMRRC:034833-JAX
Associated
Mutations,
Markers,
and QTL
2 associated mutations
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Alzheimer's disease 3 √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
MMRRC:034833-JAX MMRRC B6J.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax exact match to ID
References
  • Earliest
    J:104236 Savonenko A, et al., Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis. 2005 Apr;18(3):602-17
  • All
    6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory