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B6.Cg-Fbn1Tsk Strain Detail
Summary
  • Strain Name
    B6.Cg-Fbn1Tsk
  • Attributes
    congenic, mutant strain, spontaneous mutation
  • MGI ID
    MGI:3619982
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Fbn1Tsk Fbn1
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Marfan syndrome √
pulmonary emphysema √
systemic scleroderma √
Key √ disease model expected model not found
References
  • Earliest
    J:135507 Bayle J, et al., Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis. J Invest Dermatol. 2008 Apr;128(4):871-81
  • All
    1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory