B10.Cg-H2<h4> Sh3pxd2b<nee>/GrsrJ Strain Detail MGI Mouse MGI:3664242

B10.Cg-H2^h4 Sh3pxd2b^nee/GrsrJ Strain Detail

Summary

Strain Name

B10.Cg-H2^h4 Sh3pxd2b^nee/GrsrJ
Attributes

coisogenic, congenic, major histocompatibility congenic, mutant strain, spontaneous mutation
MGI ID

MGI:3664242
Synonyms

B6.Cg H2^h4-nee/J, B6.Cg-H2^h4-nee/J, B10.A-H2^h4/(4R)SgDvEgJ-Sh3pxd2b^nee, B10.Cg H2^h4-nee/J, B10.Cg H2^h4-Sh3pxd2b^nee/GrsrJ

2 associated mutations

Mutation Carried	Marker
H2^h4	H2
Sh3pxd2b^nee	Sh3pxd2b

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
glaucoma	√
otitis media	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:006446	JAX	B10.Cg-H2^h4 Sh3pxd2b^nee/GrsrJ	exact match to ID

Earliest

J:153369 Mao M, et al., The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development. Mamm Genome. 2009 Aug;20(8):462-75
All

3

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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