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B6.129S6-Cavin1tm1Pfp/J Strain Detail
Summary
  • Strain Name
    B6.129S6-Cavin1tm1Pfp/J
  • Attributes
    congenic, targeted mutation
  • MGI ID
    MGI:3847330
  • Synonyms
    B6.129S6-Ptrftm1Pfp/J
  • Other IDs
    JAX:010502
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Cavin1tm1Pfp Cavin1
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
pulmonary hypertension √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
JAX:010502 JAX B6.129S6-Cavin1tm1Pfp/J exact match to ID
References
  • Earliest
    J:143425 Liu L, et al., Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct;8(4):310-7
  • All
    2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory