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B6.129-Shank3tm2Gfng/J Strain Detail
Summary
  • Strain Name
    B6.129-Shank3tm2Gfng/J
  • Attributes
    congenic, mutant strain, targeted mutation
  • MGI ID
    MGI:5444207
  • Other IDs
    JAX:017688
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Shank3tm2Gfng Shank3
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
autism spectrum disorder √
Phelan-McDermid syndrome √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
JAX:017688 JAX B6.129-Shank3tm2Gfng/J exact match to ID
References
  • Earliest
    J:171113 Peca J, et al., Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature. 2011 Apr 28;472(7344):437-42
  • All
    16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory