About   Help   FAQ
B6.129-Shank3tm2Gfng/J Strain Detail
Summary
  • Strain Name
    B6.129-Shank3tm2Gfng/J
  • Attributes
    congenic, mutant strain, targeted mutation
  • MGI ID
    MGI:5444207
  • Other IDs
    JAX:017688
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Shank3tm2Gfng Shank3
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
autism spectrum disorder √
Phelan-McDermid syndrome √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
JAX:017688 JAX B6.129-Shank3tm2Gfng/J exact match to ID
References
  • Earliest
    J:171113 Peca J, et al., Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature. 2011 Apr 28;472(7344):437-42
  • All
    16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory