129S1.NON(NZO)-Col4a4<bwk>/PgnJ Strain Detail MGI Mouse MGI:5696181

129S1.NON(NZO)-Col4a4^bwk/PgnJ Strain Detail

Summary

1 associated mutation

Mutation Carried	Marker
Col4a4^bwk	Col4a4

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
autosomal recessive Alport syndrome	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:017865	JAX	129S1.NON(NZO)-Col4a4^bwk/PgnJ	exact match to ID

Earliest

J:223185 Korstanje R, et al., A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen alpha3alpha4alpha5(IV) trimers. Kidney Int. 2014 Jun;85(6):1461-8
All

1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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