NOD/ShiLtDvs-H2-K1<d-em1Dvs> H2-D1<b-em5Dvs> Tg(HLA-A/H2-D/B2M)1Dvs/Dvs Strain Detail MGI Mouse MGI:6119485

NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-D1^b-em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs Strain Detail

Summary

Strain Name

NOD/ShiLtDvs-H2-K1^d-em1Dvs H2-D1^b-em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs
Attributes

coisogenic, endonuclease-mediated mutation, mutant strain, transgenic
MGI ID

MGI:6119485
Synonyms

NOD/ShiLtDvs-H2-K1^em1Dvs H2-D1^em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs

2 associated mutations

Mutation Carried	Marker
H2-D1^b-em5Dvs	H2-D1
H2-K1^d-em1Dvs	H2-K1

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Earliest

J:346039 Racine JJ, et al., HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. J Immunol. 2023 Dec 15;211(12):1792-1805
All

1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24