About   Help   FAQ
C57BL/6J-Dis3l2em3Jtm Strain Detail
Summary
  • Strain Name
    C57BL/6J-Dis3l2em3Jtm
  • Attributes
    coisogenic, endonuclease-mediated mutation, mutant strain
  • MGI ID
    MGI:6286060
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Dis3l2em3Jtm Dis3l2
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Perlman syndrome
Key disease model expected model not found
References
  • Earliest
    J:272435 Hunter RW, et al., Loss of Dis3l2 partially phenocopies Perlman syndrome in mice and results in up-regulation of Igf2 in nephron progenitor cells. Genes Dev. 2018 Jul 1;32(13-14):903-908
  • All

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory