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B6.Cg-Rhbdf1em1Mvw Rhbdf2tm1a(KOMP)Wtsi/Mvw Strain Detail
Summary
  • Strain Name
    B6.Cg-Rhbdf1em1Mvw Rhbdf2tm1a(KOMP)Wtsi/Mvw
  • Attributes
    endonuclease-mediated mutation, mutant strain, targeted mutation
  • MGI ID
    MGI:6446984
  • Synonyms
    Rhbdf1v/v Rhbdf2-/-
  • Other IDs
    JAX:035526
Associated
Mutations,
Markers,
and QTL
2 associated mutations
Associated
Phenotypes
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
References
  • Earliest
    J:211269 Hosur V, et al., Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2200-9
  • All
    2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory