Name ID |
C57BL/6-Prf1tm1Sdz/J MGI:2162806 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal circulating cytokine level |
abnormal cytotoxic T cell physiology |
abnormal lymph node morphology |
abnormal lymphocyte physiology |
abnormal macrophage activation involved in immune response |
abnormal spleen white pulp morphology |
abnormal T cell activation |
brain inflammation |
CNS inflammation |
decreased circulating fibrinogen level |
decreased cytotoxic T cell cytolysis |
decreased interferon-gamma secretion |
decreased leukocyte cell number |
decreased neutrophil cell number |
decreased NK cell degranulation |
increased circulating interferon-alpha level |
increased circulating interferon-gamma level |
increased circulating interleukin-1 beta level |
increased circulating interleukin-6 level |
increased circulating interleukin-10 level |
increased circulating interleukin-18 level |
increased circulating tumor necrosis factor level |
increased spleen red pulp amount |
increased susceptibility to Picornaviridae infection |
increased susceptibility to Riboviria infection |
increased susceptibility to Riboviria infection induced morbidity/mortality |
increased susceptibility to viral infection induced morbidity/mortality |
liver inflammation |
lymph node inflammation |
lymph node necrosis |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
Prf1tm1Sdz/Prf1tm1Sdz |