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Name
ID
C57BL/6-Prf1tm1Sdz/J
MGI:2162806
Phenotype annotations related to immune system
Darker colors indicate more annotations
Mouse Phenotypes
abnormal circulating cytokine level
abnormal cytotoxic T cell physiology
abnormal lymph node morphology
abnormal lymphocyte physiology
abnormal macrophage activation involved in immune response
abnormal spleen white pulp morphology
abnormal T cell activation
brain inflammation
CNS inflammation
decreased circulating fibrinogen level
decreased cytotoxic T cell cytolysis
decreased interferon-gamma secretion
decreased leukocyte cell number
decreased neutrophil cell number
decreased NK cell degranulation
increased circulating interferon-alpha level
increased circulating interferon-gamma level
increased circulating interleukin-1 beta level
increased circulating interleukin-6 level
increased circulating interleukin-10 level
increased circulating interleukin-18 level
increased circulating tumor necrosis factor level
increased spleen red pulp amount
increased susceptibility to Picornaviridae infection
increased susceptibility to Riboviria infection
increased susceptibility to Riboviria infection induced morbidity/mortality
increased susceptibility to viral infection induced morbidity/mortality
liver inflammation
lymph node inflammation
lymph node necrosis
Availability Mouse Genotype
Prf1tm1Sdz/Prf1tm1Sdz