Name ID |
NOD.Cg-Prkdcscid MGI:2173972 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal lymph node morphology |
abnormal response to transplant |
abnormal spleen white pulp morphology |
abnormal thymus corticomedullary boundary morphology |
abnormal thymus lobule morphology |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased immunoglobulin level |
decreased level of surface class I molecules |
decreased lymphocyte cell number |
decreased mature B cell number |
decreased NK cell number |
decreased pre-B cell number |
decreased T cell number |
impaired complement classical pathway |
impaired natural killer cell mediated cytotoxicity |
increased granulocyte number |
increased length of allograft survival |
increased macrophage cell number |
increased T cell derived lymphoma incidence |
spleen hypoplasia |
thymus cyst |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Prkdcscid/Prkdcscid |