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Name
ID 		129S6/SvEvTac-Tnfaip8l2tm1Yhcn
MGI:3810969
Phenotype annotations related to immune system
Darker colors indicate more annotations
Mouse Phenotypes
abnormal B cell activation
abnormal B cell physiology
abnormal CD4-positive, alpha-beta T cell physiology
abnormal cytotoxic T cell physiology
abnormal inflammatory response
abnormal leukocyte morphology
abnormal macrophage activation involved in immune response
abnormal myeloid dendritic cell morphology
abnormal spleen morphology
abnormal T cell apoptosis
chronic inflammation
decreased IgG2a level
decreased IgG2b level
enlarged spleen
increased B cell number
increased circulating interleukin-1 beta level
increased circulating interleukin-6 level
increased circulating interleukin-10 level
increased circulating interleukin-12 level
increased circulating tumor necrosis factor level
increased interferon-gamma secretion
increased interleukin-1 beta secretion
increased interleukin-2 secretion
increased interleukin-4 secretion
increased interleukin-6 secretion
increased interleukin-12 secretion
increased interleukin-17 secretion
increased spleen white pulp amount
increased susceptibility to endotoxin shock
increased T cell number
increased tumor necrosis factor secretion
intestinal inflammation
liver inflammation
lung inflammation
lymph node inflammation
spleen hyperplasia
Availability Mouse Genotype
Tnfaip8l2tm1Yhcn/Tnfaip8l2tm1Yhcn