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Name
ID 		B6.129S1(Cg)-Lrrc8atm1.1Geha
MGI:5825471
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Mouse Phenotypes
abnormal B cell differentiation
abnormal T cell differentiation
abnormal T cell physiology
abnormal T cell selection
abnormal thymus apoptosis
abnormal thymus medulla morphology
abnormal thymus morphology
abnormal thymus physiology
absent thymus corticomedullary boundary
decreased B cell number
decreased CD4-positive, alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased DN2 thymocyte number
decreased DN3 thymocyte number
decreased DN4 thymocyte number
decreased double-negative T cell number
decreased double-positive T cell number
decreased immature B cell number
decreased marginal zone B cell number
decreased pre-B cell number
decreased T cell number
decreased T cell proliferation
decreased thymocyte number
decreased transitional stage B cell number
increased IgG2a level
increased pro-B cell number
increased regulatory T cell number
increased thymocyte apoptosis
small spleen
small thymus
small thymus cortex
thymus hypoplasia
Availability Mouse Genotype
Lrrc8atm1.1Geha/Lrrc8atm1.1Geha