Name ID |
C3HeB/FeJ-Psmb10Tub6 MGI:6154969 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal T cell activation |
absent lymph nodes |
absent spleen white pulp |
athymia |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased immunoglobulin level |
decreased interferon-gamma secretion |
decreased leukocyte cell number |
decreased NK cell number |
decreased spleen red pulp amount |
decreased T cell number |
increased circulating interleukin-1 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
increased granulocyte number |
increased inflammatory response |
increased susceptibility to bacterial infection induced morbidity/mortality |
skin inflammation |
|
Availability | Mouse Genotype | ||||||||||||||||||||
Psmb10Tub6/Psmb10+ | |||||||||||||||||||||
Psmb10Tub6/Psmb10Tub6 |