Name ID |
B6.129S7-Dusp22tm1Tht MGI:6379995 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal B cell activation |
abnormal cytokine level |
abnormal T cell activation |
decreased B cell proliferation |
decreased IgG3 level |
decreased IgM level |
decreased immunoglobulin level |
enlarged spleen |
increased circulating interferon-gamma level |
increased circulating interleukin-6 level |
increased circulating interleukin-17 level |
increased circulating tumor necrosis factor level |
increased inflammatory response |
increased interferon-gamma secretion |
increased interleukin-2 secretion |
increased interleukin-4 secretion |
increased interleukin-17 secretion |
increased spleen white pulp amount |
increased susceptibility to autoimmune disorder |
increased susceptibility to experimental autoimmune encephalomyelitis |
increased T cell proliferation |
kidney inflammation |
liver inflammation |
lung inflammation |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||
Dusp22tm1Tht/Dusp22tm1Tht |