Name ID |
C57BL/6J-Snrnp40em1Btlr/Snrnp40swp MGI:6696345 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal CD4-positive, alpha-beta T cell physiology |
abnormal CD8-positive, alpha-beta T cell physiology |
abnormal thymus development |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased DN1 thymic pro-T cell number |
decreased DN4 thymocyte number |
decreased lymphocyte cell number |
decreased monocyte cell number |
decreased NK cell number |
decreased T cell number |
decreased T cell proliferation |
impaired natural killer cell mediated cytotoxicity |
increased central memory CD8 positive, alpha-beta T cell number |
increased circulating interferon-beta level |
increased circulating interferon-gamma level |
increased circulating interleukin-6 level |
increased circulating interleukin-12 level |
increased circulating interleukin-17 level |
increased circulating tumor necrosis factor level |
increased effector memory CD8-positive, alpha-beta T cell number |
increased susceptibility to viral infection |
increased susceptibility to viral infection induced morbidity/mortality |
small thymus |
thymus hypoplasia |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||
Snrnp40em1Btlr/Snrnp40swp |