Index
Click on a letter above to jump to that section of the Index.
aboriginal species
2.3.1,
2.3.5
Africa
2.2.2
allele-specific oligonucleotides
8.3.2.2,
10.1.1,
Appendix E: Glossary of Terms
Alu elements, human
5.4.4
AMAN
Appendix B3.2
America
1.1.1
anchor loci
8.3.6.1,
9.3.1,
9.3.4,
9.4.4.2,
10.1.1,
Appendix E: Glossary of Terms
anonymous DNA locus
3.4.3,
7.1.1,
8.2.2,
8.3.6.5,
Appendix E: Glossary of Terms
antibodies
7.4.1,
7.2.4.2,
7.3.4
antigens as genetic markers
7.2.4.2,
7.3.4
Arabidopsis
9.2.1.1
artificial insemination
2.3.5,
4.5.1
ASOs, see
allele-specific oligonucleotides
Avner, Philip
7.2.4.4
B1 elements
5.4.2,
8.3,
8.3.5,
8.3.6.3,
8.4.3,
10.2.2.2,
Appendix E: Glossary of Terms
B2 elements
5.4.2,
8.3,
8.3.5,
8.3.6.3,
8.4.3,
10.2.2.2,
Appendix E: Glossary of Terms
B6, see
strain C57BL/6
B10, see
strain C57BL/10
backcross analysis
9.4.1
illustration
Figure 9.11
backcrossing
3.2.1,
3.3.2,
3.3.3,
3.3.4,
7.2.2.1,
Appendix E: Glossary of Terms;
Table 3.2;
Figures
3.4,
3.5,
3.6
Baekon, Inc.
Appendix A
Bailey, Donald
7.2.4.2,
9.2.1.1
Bayesian analysis
9.1.3.6,
9.2.2.2,
9.2.2.3,
9.4.4.2,
Appendix E: Glossary of Terms
binomial formula
Appendix D1.2
biotinylation
8.3.2.3
Birkenmeier, E.
9.3.3
blending inheritance
1.2.1
Bonhomme, Françoise
2.3.2,
2.3.3,
2.3.5,
7.2.4.3,
9.3.1
Brave New World
1.3.3
Brown, Stephen
9.3.3
Bruce effect
4.3.7
Burke, David
10.3.3.1
Bussey Institute
1.2.2
CA-repeats
8.3.6.1,
8.3.6.5,
Appendix E: Glossary of Terms
Caenorhabditis elegans
1.2.3,
1.3.1
California
2.2.3
Cambrian explosion
1.3.1
cancer
1.2.3
candidate gene approach
6.3.1,
9.3.4
Cappechi, Mario
6.4.1
Carter, T.C.
6.1.1
Castle, William
1.1.2,
1.2.2
cat
1.1.2
centromeres
5.3.1.1,
5.3.4,
5.4.4,
7.2.3.1,
9.1.2,
9.1.2.2,
9.1.2.3,
9.1.2.4,
10.2.2.1
cesium chloride gradient centrifugation
5.3.4
Chapman, Verne
2.3.5
Charles River Laboratory
3.1,
Appendix A
Chi-squared analysis
9.1.3.3,
9.1.3.4,
Appendix E: Glossary of Terms
backcross data
9.1.3.3
intercross data
9.1.3.4
limitations
9.1.3.5
recombinant inbred data
9.2.2.3
table of P values
9.1.3.3,
Table 9.1
chiasmata
5.1.3
chimeras, interspecific
5.3.4,
6.2.1,
6.4.1,
Appendix E: Glossary of Terms
China
2.2.2
chlorambucil
6.1.2,
7.3.5
chromosome
17:
5.5.1,
9.2.2.4,
10.1.2
aberrations
5.5.1
assignment
7.1.2,
9.1.1,
10.2.2.1,
10.2.3.1
disjunction
5.2.3.1,
5.2.3.2
DNA content
5.2.1.3
lengths
5.2.1.3,
9.4.4.2
map
7.1.3
metacentric
5.2.2.1
microdissection
8.4.1
nondisjunction
5.2.3.1,
5.2.3.2,
5.2.3.3
walking
10.3.3.2,
Appendix E: Glossary of Terms
X
5.3.3.2
Y
2.3.4,
5.3.3.2
civilization
1.1.1,
2.2.2
coat colors
8.1
coisogenic strains
3.3.2,
3.3.3.2,
Appendix E: Glossary of Terms
Cold Spring Harbor Laboratory
1.2.2,
7.2.4.3
Collins, Francis
10.4
commensal animals
2.2.2,
2.3.1,
2.4.2,
Appendix E: Glossary of Terms
Committee on the Standardized Nomenclature for Mice
3.2.2,
3.4.1,
3.4.6
complementation analysis
7.3.5
complex traits
7.4.3
computer programs
Appendix B3.1,
Appendix D1.3
concordance
9.2.2.2,
Appendix E: Glossary of Terms
complete
9.4.5,
10.3.1,
Appendix D1.1
confidence interval
9.2.4.2,
Appendix D1.1
congenic strains
3.3.3.1,
3.3.3.2,
3.3.3.3,
3.3.4.2,
8.4.4,
9.1.2.3,
Appendix E: Glossary of Terms
conplastic strains
3.3.3.5,
Appendix E: Glossary of Terms
conservation, mouse versus humans
10.3.4.5
consomic strains
3.3.3.4,
Appendix E: Glossary of Terms
contamination, monitoring of
2.3.4,
8.3.4
contig
8.4,
10.3.3.1,
Appendix E: Glossary of Terms
Copeland, Neil
9.3.1,
9.3.3
copulation
4.3.2
Cot curve
5.1.2,
5.1.5.2
Cot values
5.3.4
CpG dinucleotide
8.2.2,
10.3.2,
10.3.4.4
CpG islands
10.3.4.4,
Appendix E: Glossary of Terms
Cretaceous extinction
2.2.1
cross-hybridization
gene families
5.3.1.2
interspecific
1.3.1,
5.3.4,
10.3.4.5
transcripts
5.1.5.2
crossing over
double
7.2.2.3
nonrandom
7.2.3.1
cryopreservation
6.1.3
Cuénot, F.
1.2.1
culling litters
4.4.3
cytogenetic map
7.1.3
database
electronic
Appendix B1.1
human genetics
Appendix B1.3
microsatellite
Appendix B1.2
mouse genetics
7.3.5,
Appendix B1.2
program for recordkeeping
3.5.5
Davisson, Muriel
6.1.3,
Appendix B1.2
DdeI
9.1.2.1
deletions
7.3.5,
8.1,
8.3.1.1
demes
2.4.2,
Appendix E: Glossary of Terms
denaturing gradient gel electrophoresis
8.3.3.2
Department of Energy
10.4
differential chromosome segment
3.3.3.2,
Appendix E: Glossary of Terms
differential locus
3.3.3.2
dinosaurs, extinction of
2.2.1
disomies, uniparental
5.2.3.3
dispersed repetitive elements, see
B1,
B2, and
LINE-1 elements
distortion of transmission ratio
6.2.5.2
diversity, generation of
10.1.2
DNA elements, copy number
5.3.1.2
DNA fingerprinting
8.2.3,
8.3.4
DNA marker panels
7.3.2,
8.4,
10.2.3.1,
Appendix E: Glossary of Terms
DNaseI hypersensitive sites
10.4
domestication
1.1.2
Doolittle, D.P.
Appendix B1.2
Drosophila melanogaster
chromosome microdissection
8.4.1
deletion mutations
6.1.2
homeobox genes
5.3.3.1
linkage map
7.2.1
model organism
1.2.3,
1.3.1
recombination
7.2.3.2,
7.2.3.3
Dunn, L.C.
1.2.2,
3.5.3
duplications
8.1
EcoRI
5.4.2,
8.2.2
eggs
4.2.2,
4.3.1,
4.3.2,
4.3.3,
4.3.4
Egypt
1.1.2
Eicher, Eva
5.2.3.1
embryo, manipulation
1.3.3,
4.5.3
embryonic stem cells
6.2.1,
6.3.1,
6.4.1,
6.4.2,
Appendix E: Glossary of Terms
episodic amplification
5.4.2,
5.4.3
estrus cycle
4.3.1,
4.5.1
estrus, postpartum
4.4.6
ethylnitrosourea
6.1.2
European Collaborative Interspecific Backcross
9.3.3
evolution
concerted
5.3.3.1,
5.3.3.3,
5.4.2
genome
5.3.1,
5.3.2,
5.3.3,
5.3.4,
5.4,
5.5
mammals
2.2.1
exon trapping
10.3.4.3
expressivity, variable
9.2.5.1,
9.2.5.2,
Appendix E: Glossary of Terms
F1 hybrids
3.2.6,
4.1,
4.4.7,
6.2.2.1,
6.2.3,
6.2.5.1,
9.4.1,
9.4.4.2,
Appendix E: Glossary of Terms
FACS, see
fluorescence-activated cell sorter
fancy mouse
1.1.2,
2.3.4,
3.2.3,
6.1.1,
8.1
fecundity, relative
4.1
feral animals
2.3.1,
2.4.1,
Appendix E: Glossary of Terms
Fertile Crescent
1.1.1,
2.2.2
fertilization
4.2.2,
4.3.1,
4.3.2,
4.3.3,
4.3.4
FISH
5.4.4,
10.2.1,
10.2.2,
Appendix E: Glossary of Terms
fluorescence-activated cell sorter
5.2.2.2,
8.4.2
follicles
4.2.2,
4.3.2
forced heterozygosity
3.2.4,
3.3.3.2
fossils
1.3.1,
2.2.2
foster mothers
4.4.4
framework map
8.2.3,
8.3.6.1,
9.4.4
G-bands
5.2.1.1,
5.4.4
Gall, Joseph
5.3.4
Galton, Francis
1.2.1
gametogenesis
5.5.1
GenBank
7.4.1,
8.3.6.3,
8.3.6.5,
Appendix B1.3
gene
agouti (A)
7.2.2.1,
10.2.3.2,
see also
MGI
albino (c)
6.1.1,
6.4.5,
7.2.4.1,
see also
MGI
alpha-globin (Hba)
5.1.5.1,
5.3.3.1,
see also
MGI
beta-globin (Hbb)
5.1.5.1,
5.3.3.1,
5.3.3.2,
see also
MGI
brown (b)
6.1.1,
see also
MGI
dilute (d)
6.1.1,
see also
MGI
Duchene's muscular dystrophy (DMD)
5.1.5.1,
see also
MGI
dwarf (dw)
4.5.2,
see also
MGI
H2
3.3.3.1,
5.3.2.4,
5.3.3.1,
10.1.2,
see also
MGI
H19
5.5.1,
see also
OMIM
histone family
5.3.3.3
Hox family
5.3.3.1,
see also the MGI entries for
Hoxa,
Hoxb,
Hoxc, and
Hoxd
IAP
5.4.1,
see also
MGI
Igf2
5.5.1,
see also
MGI
Igf2r
5.5.1,
see also
MGI
immunoglobulin family
5.3.3.1,
see also the MGI entries for
Igh,
Igk and
Igl
MHC
3.3.3.1,
5.3.2.4,
5.3.3.1,
10.1.2,
see also
MGI
muscular dystrophy (mdx)
5.1.5.1,
see also
MGI
myoglobin (myg)
5.3.3.1,
see also
MGI
obese (ob)
4.5.2,
see also
MGI
ornithine decarboxylase
8.2.4,
see also
MGI
piebald (s)
6.1.1,
see also
MGI
pink-eyed dilution (p)
6.1.1,
6.4.5,
7.2.4.1,
see also
MGI
ribosomal RNA
5.3.3.3,
10.2.2.1
short-ear (se)
6.1.1,
see also
MGI
Steel (Sl)
6.4.5,
see also
MGI
T-cell receptor (Tcr)
5.3.3.1,
see also
MGI
T locus
6.1.1,
6.2.5.2,
7.2.2.1,
see also the MGI entries for
T and
t
transfer RNA
5.3.3.3
triose phosphate isomerase
8.2.4,
see also
MGI
VL30
5.4.1
W locus
6.1.1,
see also
MGI
gene conversion
5.3.2.4,
5.3.3.3
gene dosage effects
5.2.3.3
gene duplication
5.3.2.1
gene expression
spatial sequence
5.3.3.1,
5.3.3.2
temporal sequence
5.3.3.2
gene families
5.3.1.2,
5.3.3,
8.2.4
gene function
7.4.1,
7.4.2,
7.4.3
gene identification
10.3.4
cDNA slection
10.3.4.1
exon trapping
10.3.4.3
by sequencing
10.3.4.6
zoo blots
10.3.4.5
gene knockouts, see
targeted mutagenesis
GENE-LINK
Appendix B3.1
gene order, conservation of
10.2.1
gene order, significance of
5.3.3.2
gene replacement, see
targeted mutagenesis
gene targeting, see
targeted mutagenesis
gene trapping
6.5.1
genes
definition
7.1.1.1
evolutionary conservation
5.1.4
housekeeping
5.2.1.1
median size
5.1.5.1
number in genome
5.1.5
paralogous
5.3.3.1
tissue-specific
5.2.1.1
vital function
5.1.5.1
genetic code
5.3.2.1
genetic diseases, human
5.5.1
genetic drift
5.2.2.1,
5.3.1.1,
5.3.2.1,
5.3.3.3,
5.4.2,
5.4.3,
10.3.4.5,
Appendix E: Glossary of Terms
genetic maps
7.1.1.2,
7.1.2,
7.1.3,
7.1.4,
7.1.5
genetic monitoring
8.3.4
genome
complexity
5.1.2
evolution
5.3,
5.4,
5.5
haploid content
5.1.1
human
1.3.1
long range structure
5.2.1.1
mammals
1.3.1
mitochondrial
2.3.3,
3.3.3.5
mouse-human comparison
1.3.1,
5.1.5.1
organization
5.3.1.1,
5.3.1.2,
5.3.3.2
quantification
5.1
size in ancestor
5.3.2.1
whole linkage map
2.3.5
Genome Database, Human
7.3.5,
Appendix B1.3
genome scanning, whole
8.2.5,
8.3.6.5
genomic imprinting
5.2.3.3,
5.5,
6.2.1,
10.4,
Appendix E: Glossary of Terms
GenPharm
Appendix A
gerbil
2.1
germ cells, male
4.2.1
germ line integration
5.4.1
Germany
2.2.2
gestation
4.3.6,
4.3.7,
4.4.7
Giemsa staining
5.2.1.1,
Appendix E: Glossary of Terms
Gopher
Appendix B1.1
Green, Earl
3.2.2
Green, Margaret
6.1.3,
Appendix B1.2
Guènet, Jean-Louis
8.2.2,
9.3.3
guinea pig
2.1
H2 complex
3.3.3.1
habitat, natural
2.4.1
Haig, David
5.5.2
hairpin loops
5.4.3
Haldane, J.B.S.
7.2.2.3,
7.2.4.1
Haldane-Waddington equation
9.2.2.3,
9.2.4.1,
9.2.4.3,
Appendix D1.1,
Appendix D1.2
haplo-insufficiency
6.1.1
haplotype analysis
9.4.4.5
haplotypes
10.1.1,
Appendix E: Glossary of Terms
Harlan Sprague Dawley
3.1,
Appendix A
Harvard University
1.2.2
Harwell, England
1.2.3,
6.1.1
heterochromatin
5.4.4
Hilltop Labs
Appendix A
histocompatibility
3.3.3.1,
Appendix E: Glossary of Terms
history
129 strain
6.4.5
classical genetics
7.2.1
congenic strains
3.3.3.1
DNA cloning
7.2.4.3
house mouse
1.1.1,
1.1.2
in situ hybridization
10.2.2.1
inbred strains
2.3.4
interspecific cross
2.3.5,
7.2.4.3,
9.3.1,
9.3.2,
9.3.3,
9.3.4
linkage map
7.2.2.1
microsatellites
7.2.4.4,
8.3.6.1
mouse genetics
1.2.1,
1.2.2,
1.2.3,
7.2.4.1,
7.2.4.2,
7.2.4.3,
7.2.4.4,
Notes
mutagenesis
6.1.1
recombinant inbred strains
7.2.4.2,
9.2.1.1
somatic cell hybrid analysis
10.2.3.1
targeted mutagenesis
6.4.1
transgenics
6.3.1
hit and run technique
6.4.3
Holliday model
5.3.2.4
hotspots
for mutation
8.2.2
of recombination
7.2.3.3,
9.4.2.1,
10.2.3.2,
Appendix E: Glossary of Terms
human diseases
6.4.1
Human Genome Project
10.4
hybrid vigor
3.2.6,
4.1,
6.2.2.1,
6.2.3,
9.4.1,
9.5.3
hybrid zomes
2.3.3,
Appendix E: Glossary of Terms
hybridization
allele-specific oligonucleotides
8.3.2.2
cross-species
1.3.1,
10.3.4.5
in situ
5.2.2.2,
5.3.4,
5.4.4,
7.1.3,
7.3.2,
9.1.1,
9.1.2.4,
9.2.2.4,
10.2.2,
Appendix E: Glossary of Terms
substractive
8.4.4
theoretical considerations
8.3.2.1
hypermedia
Appendix B1.1
IBM
Appendix B1-1
ice age
1.1.1
ID elements
5.4.4
idiogram
5.2.1.2,
Figure 5.2
immunology
1.2.3
implantation
4.3.7
in vitro fertilization
4.5.3
inbreeding
3.2.2,
3.2.3,
3.2.4,
3.2.5,
3.2.6,
Appendix E: Glossary of Terms
depression
3.2.5
incross
3.2.1;
Table 3.2;
Appendix E: Glossary of Terms
India
2.2.2
insertional mutagenesis
6.3.1,
6.5.1
insertions
8.3.1.1,
Figure 8.7
intercross
3.2.1;
Table 3.2;
Appendix E: Glossary of Terms
intercross analysis
9.4,
9.5
advantages
9.4.3.2
illustration
Figure 9.12
intercross mapping
8.3.4
interference, genetic
7.2.2.3,
9.2.2.4,
9.4.3.1,
Glossary of Terms
Internet
Appendix B
interspecific backcross
8.2.1,
8.2.4,
9.1.1,
9.1.2.4,
9.2.2.4,
9.3,
9.4.2.1
history
2.3.5,
7.2.4.3
inversion polymorphism
9.3.2.1
interspecific cross
2.3.3,
2.3.4,
2.3.5,
3.3.3.5,
4.3.4,
4.5.1,
8.3.6.5,
Glossary of Terms
interspersed repetitive sequence PCR
8.3.5,
8.4.3,
Glossary of Terms
intracisternal A particle elements
5.4.1,
8.2.4
introgression
2.3.3
inversion, chromosomal
2.3.5,
7.3.5,
8.1,
8.3.1.1,
Figure 8.7,
9.3.2.1,
9.4.2.1
IRS-PCR, see
interspersed repetitive sequence PCR
isozyme mapping
7.2.4.2,
7.3.4
Jackson Laboratory
1.2.2,
1.2.3,
2.3.5,
3.1,
3.2.5,
4.4.7,
4.5.2,
5.2.2.2,
6.1.3,
6.4.5,
6.5.2,
7.2.4.2,
7.3.1,
7.3.5,
9.2.1.1,
9.2.1.2,
9.3.2.2,
9.3.4,
9.4.2.2,
Appendix A,
Appendix B1.2
Japan
Figure 2.3,
2.2.3,
2.3.3
Jeffreys, A.
8.2.3
Jenkins, Nancy
9.3.1,
9.3.3
Johns Hopkins University
Appendix B1.3
karyotype
9.1.2,
9.1.2.2,
10.2.2.1,
10.2.3.1,
Glossary of Terms
aberrant
7.3.5
standard mouse
2.3.5,
5.2.1.1,
5.2.1.2,
Figure 5.2
lactation
4.4.3
Lathrop, Abbie
1.1.2,
2.3.4,
3.4.2
lethal dose 50 determination
9.2.5.1
libido
4.3.3
library
bacterial artificial chromosome
10.3.3.1
bacteriophage P1
10.3.3.1
CA-repeats
8.3.6.5
cDNA
7.4.1,
8.3.1.2
chromosome-specific
7.3.3,
8.4
cosmid
7.1.4,
8.3.6.5
deletions
6.1.2
genomic
5.4.4,
Glossary of Terms
129 genomic
6.4.4
large-insert
8.4.2
microsatellite detection
8.3.6.2
ordered
8.4
YAC
1.3.4,
6.5.3,
7.1.4,
8.3.6.5,
10.3.3.1,
Glossary of terms
Life Sciences Inc.
Appendix A
life span
4.4.7
ligase chain reaction
8.3.2.4
ligase-mediated gene detection
8.3.2.3
LINE-1 elements
5.2.1.1,
5.4.2,
5.4.3,
5.4.4,
8.3,
8.3.6.3,
8.4.3,
10.2.2.2
linkage
7.2.2,
Glossary of Terms
linkage distances
7.2.2.2,
7.2.2.3,
7.2.3.1,
7.2.3.2,
7.2.3.3
linkage group
7.2.2.2,
Glossary of Terms
linkage map
computer analysis
Appendix B3.1
high resolution
10.3.1,
10.4
mitotic
10.1.2
size
5.1.3
whole genome
5.1.3
linkage mapping
9.1.1,
10.2.3.2
general strategies
7.3
mutations
7.3.5
novel DNA clones
7.3.1
polypeptide loci
7.3.4
region-specific markers
7.3.3
sperm typing
10.1.1
statistical analysis
9.1.3
transgene insertion sites
7.3.2
Little, Clarence
1.2.2
locus control region
5.3.3.2
locus, definition
7.1.1.1,
Glossary of Terms
LOD score
9.1.3.2
Lyon, Mary
1.2.3
M. abbotti
2.3.5,
Figure 2.2
M. brevirostris
2.3.2
M. caroli
2.2.2,
5.3.4,
Figure 2.2
M. cervicolor
5.3.4,
Figure 2.2
M. cookii
2.3.5,
5.3.4,
Figure 2.2
M. hortulanus
2.3.5,
3.2.5,
Figure 2.2
M. m. bactrianus
2.2.2,
2.3.2,
2.3.4,
5.2,
Figure 2.2
M. m. castaneus
2.2.2,
2.3.2,
2.3.4,
3.2.5,
5.2.1.1,
8.2.1,
8.3.6.4,
9.3.2.1,
9.4.2.1;
Table 3.1;
Figure 2.2
M. m. domesticus
2.2.2,
2.3.2,
2.3.3,
2.3.4,
2.3.5,
5.2,
9.4.2.1,
Figure 2.2
M. m. molossinus
2.2.3,
2.3.3,
2.3.4,
3.2.5,
9.4.2;
Table 3.1;
Figure 2.3
M. m. musculus
2.2.2,
2.3.2,
2.3.3,
5.2.1,
9.4.2.2,
Figure 2.2
M. macedonicus
2.3.5,
5.2,
Figure 2.2
M. poschiavinus
2.3.2,
5.2.2
M. spiceligus
2.3.5,
3.2.5,
5.2,
Figure 2.2
M. spretus
2.3.5,
3.2.5,
5.2,
5.3.4,
7.2.4.3,
8.1,
8.2.1,
8.2.2;
Table 3.1;
Figure 2.2
Macintosh computer
Appendix B1.1,
Appendix B3.1,
Appendix B3.2
major histocompatibility complex
3.3.3.1
Map Manager
9.2.2.1,
9.2.2.4,
9.2.3,
9.3.2.2,
9.4.3.1,
9.4.3.2,
9.4.4.3,
9.4.4.5,
Appendix B3.1
Mapmaker
9.4.3.2,
Appendix B3.1
mapping
breakpoints
10.2.2.2
centromeres
9.1.2,
10.2.2.2
mutations see
mutation mapping
statistical analysis
9.1.3
synteny
10.2.1
telomeres
9.1.2
transgene loci
10.2.2.2
mapping function
9.2.2.3
Carter-Falconer
7.2.2.3,
9.4.4.2,
9.4.4.5,
Figures
9.13,
9.15
Haldane
7.2.2.3
Kosambi
7.2.2.3
mapping panels
7.3.1,
9.1,
9.2,
9.3,
9.4
choice of cross
9.3.2
genetic considerations
9.3.2.1
strain choice
9.4.2.1
maps
7.1.3,
7.1.5
cytogenetic
7.1.3,
7.1.5
linkage
7.1.2,
7.1.5,
7.2
physical
7.1.4,
10.3,
Figures
7.5,
10.1
whole genome
2.3.5,
7.2.4.3,
9.1.1.1
maximum likelihood estimation
9.1.3.2,
9.4.3.2,
9.4.4.5,
Appendix B3.1
McKusick, Victor
Appendix B1.3
Medical Research Council, Harwell, England
1.2.3,
6.1.1
meiosis
4.2.1,
Appendix E: Glossary of Terms
Mendel's laws
1.2,
5.2.3.2,
7.2.1
methylation
8.2.2
10.3.4.4,
10.4
Mickey Mouse
1.1.1,
1.1.2
microdissection, chromosome
5.2.2.2,
8.4.1,
Appendix E: Glossary
microinjection
6.3.1
microsatellites
5.4.5,
8.3.6,
Appendix E: Glossary of Terms
anchor loci
1.3.4,
9.4.4.2
classification
8.3.6.3
database
Appendix
B1.1,
B1.2
frequency of occurrence
8.3.6.3
generation
Figure 8.4
high resolution mapping
9.4.5
history
7.2.4.4
mutation rate
8.3.6.4
polymorphism level
8.3.6.4,
9.4.2.1
Middle East
1.1.1
milk
4.4.3
minisatellites
5.4.5,
8.2.3,
Appendix E: Glossary
generation
Figure 8.4
mismatch repair
5.3.2.4
MIT
8.3.6.5,
Appendix B1.1
mitochondrial genome
2.3.4,
3.3.3.5
mitosis
4.2.2
mitotic linkage maps
10.1.2
MMTV elements
8.2.4
model organism
1.3.2
molecular clock
5.3.2.1,
5.3.3.3,
10.3.4.5
Morgan, T.H.
7.2.1
Moriwaki, K.
2.3.2
Mosaic
Appendix B1.1
mouse, definition of
2.1
mouse colony management program
Appendix B3.2
Mouse Genome Database
7.3.5,
9.3.4,
Appendix B1.2,
See also
MGI
Mouse Mutant Resource
6.1.3
Mouse Newsletter
1.2.3
MspI
8.2.2
Muller, H.
6.1.1
multifactorial traits
7.4.3,
9.5,
Appendix E: Glossary of Terms
MuLV elements
8.2.4
mutagenesis, saturation
5.1.5.3,
6.1.2
mutation
3.4.4,
Appendix E: Glossary of Terms
coat color
6.1.1
deletions
6.1.2
skeletal
6.1.1
mutation mapping
9.4
breeding scheme choice
9.4.3
gene order determination
9.4.4.5
high resolution analysis
9.4.5
linkage determination
9.4.4.3,
9.4.4.4
strain choice
9.4.2
National Institutes of Health
3.1,
10.4
Neolithic transition
1.1.1,
2.2.2
Neumann, Paul
9.2.2.3
neural nets
10.3.4.6
Nobel Prize
3.3.3.1
nomenclature
alleles
3.4.4
coisogenic strains
3.3.2
congenic strains
3.3.3.3
genes
3.4.3
genotypes
7.2.2.1,
7.2.2.2
locus symbols
3.4.3
pseudogenes
3.4.3
recombinant inbred strains
3.3.4.1,
9.2.1.2
Robertsonian chromosomes
5.2.2.1
standardized
3.4
targeted mutations
3.4.4
transgenes
3.4.5
normal distribution
Appendix D1.2
Northern blots
10.3.4.1
NotI
8.2.5,
8.4.4,
10.3.2,
10.3.4.4
nuclear transplantion
5.5.1,
6.2.1
null hypothesis
9.1.3.3,
9.1.3.4,
9.1.3.5,
9.1.3.6
nursery rhymes
1.1.1
Oak Ridge National Laboratory
1.2.3,
6.1.1
oligonucleotide
allele-specific
8.3.2.2,
8.3.2.3,
8.3.2.4
degenerate
5.3.1.2
ligation assay
8.3.2.3,
8.3.2.4
microsatellite
8.3.6.2,
8.3.6.3,
8.3.6.4
random
8.3.4
retroviral subfamilies
8.2.4
simple sequence
8.3.6.1
species-specific
8.4.4
telomere
9.1.2.1
Olson, Maynard
10.3.3.1
oocytes
4.2.2,
9.1.2.3
oogenesis
5.5.3
orphons
5.3.3.1
outbred stocks
3.2.7,
4.1
outcross
3.2.1,
Appendix E: Glossary of Terms
ovarian teratomas
9.1.2.3
ovary
4.2.2
transplantation
4.5.2
oviduct
4.3.4
ovulation
4.3.1
Pakistan
1.1.1,
2.2.2
palpation for pregnancy determination
4.3.5
Pardue, Mary Lou
5.3.4
parthenogenesis
5.5.2,
6.2.1
partial digestion
10.3.2,
10.3.4.4
passenger loci
3.3.3.2
penetrance, incomplete
9.2.5,
9.4.4.4,
Appendix E: Glossary of Terms
peptide motifs
7.4.1
Persia
1.1.2
PFGE, see
pulsed field gel electrophoresis
phase of linkage
7.2.1,
9.1.3.2
phylogenetic tree
1.3.1,
2.3.5,
Appendix E: Glossary of Terms,
Figures
1.3,
2.2
physical maps
10.3
polygenic traits
1.2.1,
3.2.5,
4.4.7,
7.4.3,
9.2.5.2,
9.5,
Appendix E: Glossary of Terms
polymerase chain reaction
1.3.3,
5.3.1.2,
9.1.1
cDNA selection
10.3.4
centromere mapping
9.1.2.4
detection of polymorphisms
8.3
interspersed repetitive sequence
8.3.5
screening YAC libraries
10.3.3.1
single sperm
10.1.1
pooling DNA samples
9.4.4.4,
9.5.4.2
positional cloning
7.4.2,
8.4,
9.4.3.3,
9.4.5,
10.3
predisposition loci
9.2.5
pregnancy
4.3.3,
4.3.4,
4.3.5,
4.3.6,
4.3.7
block
4.3.7
probability density function
Appendix D1.1
probability distribution, non-normal
9.2.4.2
pronuclei, prominent
6.2.2.2
pseudogenes
3.4.3,
5.1.4,
5.3.1.1,
5.3.2.1,
5.3.2.4,
5.3.3.1,
Figure 5.4
pseudopregnancy
3.2.7,
4.3.2,
4.5.1,
6.2.5.1,
6.2.5.2
puberty
4.3.1,
4.3.2
pulsed field gel electrophoresis
7.1.4,
10.3.2,
Appendix E: Glossary of Terms
Punnet, R.C.
7.2.1
Punnet square
9.1.3.4,
Figure 9.3
quantitative trait loci
Appendix D2
quantitative traits
7.4.3,
9.4.4.4,
9.5,
Appendix E: Glossary of Terms
R-bands
5.2.1,
5.4.4
radiation hybrid analysis
10.2.3.2
radiation-induced mutations
1.2.3,
6.1.1,
6.1.2,
7.3.5
random amplification of polymorphic DNA, see
RAPD loci
range
geographic
1.1.1,
2.2.2,
2.3.3;
Table 2.1
home
2.4.1
RAPD loci
8.3.4
rare variant alleles, detection of
8.3.3.2
rats
2.2.2
recombinant congenic strains
3.3.4.2,
Appendix E: Glossary of Terms
recombinant inbred strains
3.3.4.1,
9.1.1,
9.2,
Appendix D1,
Appendix E: Glossary of Terms
AXB/BXA sets
9.2.1.2,
9.2.5.1
BXD set
8.2.4,
8.2.5,
8.3.6.4,
9.2.1.2,
9.2.2.4,
9.2.3,
9.2.4.3,
Appendix D1.2,
Figure 9.6
comparison with backcross
9.2.4.4
complete concordance
9.2.4.3
complex trait analysis
9.2.5
construction
9.2.1.2,
Figure 9.4
CXB set
9.2.1.2
data matrix
9.2.2.4,
9.2.3,
Figure 9.6
framework maps
9.2.5.1
history
7.2.4,
9.2
linkage determination
9.2.2
map distance accuracy
9.2.4.2
map distance determination
9.2.4
map order determination
8.2.4
mapping endogenous retroviral elements
8.2.4
minisatellite polymorphism
8.2.3
naming
9.2.1.2
special properties
9.2.1.3
statistical considerations
9.2.2.2,
9.2.2.3,
Figure 9.5
table of established sets
Table 9.3
recombination
5.3.2.4,
7.2.2
rates, gender-specific
7.2.3.2,
9.4.4.2
significance
10.1.2
suppression, interspecific backcross
9.3.2.1
record-keeping
3.5
registration code
3.4.3
renaturation kinetics
5.1.2
reporter gene
6.3.1
beta-galactosidase
6.5.1
representational difference analysis
8.4.4
reproductive fitness
4.1
Research Genetics, Inc.
8.3.6.5,
9.4.4.2,
10.3.3.1
restriction enzymes, rare-cutting
10.3.2
restriction fragment length polymorphisms
8.2,
9.3.1,
Appendix E: Glossary of Terms
choice of restriction enzymes
8.2.2
difficulty with
8.3.6.1
history
7.2.4.3
molecular basis
8.2.1
rates for different strains
9.4.2.1
restriction landmark genome scanning
8.2.5
restriction maps, genomic
10.3.2
restriction site polymorphisms, PCR detection
8.3.1.1,
8.3.1.2,
Figure 8.6
retroposon
5.3.2.2,
5.4.2,
5.4.3,
5.4.4,
Appendix E: Glossary of Terms
retrotransposition
5.3.3.1,
5.4
retroviruses
endogenous
5.4.1,
8.2.4
evolutionary origin
5.4.2
reverse transcriptase
5.3.2.2
RFLP, see restriction fragment length polymorphism
Russell, L.
1.2.3
Russell, W.L.
1.2.3,
6.1.1
Russia
2.2.2
Sage, Richard
2.3.2
satellite, minor
5.3.4
satellite DNA
5.1.2,
5.3.4,
5.4.4,
9.1.2.2,
9.1.2.4,
10.2.2.1,
Appendix E: Glossary of Terms
SDP, see strain distribution pattern
segregating inbred strains
3.2.4
Seldin, Mike
9.3.3
selectable markers
6.4.2
selection, evolutionary
5.2.2.1
selective genotyping
9.5.4.2
selfish DNA, limitations
5.4.4
selfish genes
5.3.1.1,
5.3.2.2,
5.4
sequencing
10.3.4.6,
10.4
sex, determination of
4.4.2
shelter
1.1.1
Silver, J.
9.2.2.3
simple sequence length polymorphism, see
microsatellite
simple sequence repeat, see
microsatellite
SINE elements
5.2.1.1,
5.4,
8.3,
8.3.6.3,
8.4.3,
10.2.2.2,
Appendix E: Glossary of Terms -
B1 repeat,
B2 repeat,
SINE
single basepair changes
8.3.2,
8.3.3,
8.3.4
single strand conformational polymorphism
8.3.3,
10.1.1,
Appendix E: Glossary of Terms
Smithies, Oliver
6.4.1
Snell, George
1.2.2,
3.3.3.1
somatic cell hybrids
7.1.3,
7.3.4,
8.3.5,
8.4.3,
9.1.1,
9.2.2.4,
10.2.3,
10.3.3.2
Southern blots
5.3.1.2,
8.2.1,
8.2.3,
8.2.4,
8.3.3.2,
9.1.1,
9.1.2.1,
9.1.2.4,
9.3.1,
10.3.4.4,
10.3.4.5
species names
Table 2.1
Specific Locus Test
6.1.1
sperm genotyping
10.1.1
spermatogenesis
4.2.1,
5.5.3,
6.1.2
SSCP, see
single strand conformation polymorphism
SSLP, see
microsatellite
SSR, see
microsatellite
statistical analysis
9.1.3,
Appendix D1
Bayes' correction
9.1.3.6,
9.2.2.3,
9.4.4.2,
Figures
9.5,
9.13
mouse vs. human data
9.1.3.2
Stevens, Leroy
6.4.5
strain
129:
2.3.4,
6.2.3,
6.4.2,
6.4.5,
8.2.3;
Tables
3.1,
4.1;
Figure 3.3
A/J
6.2.3,
9.2.1.2,
9.2.5.1;
Table 4.1
AKR
Table 4.1
B6D2F1
6.2.3
BALB/c
1.2.2,
2.3.4,
3.1,
3.4.2,
4.1,
6.2.3,
9.2.5.1;
Tables
3.1,
4.1
C3H
1.2.2,
3.1,
4.1,
6.2.3,
8.2.3,
8.3.6.4;
Tables
3.1,
4.1
C5BL/6 (B6)
1.1.2,
1.2.2,
2.3.4,
3.1,
3.4.2,
4.1,
6.2.3,
6.4.2,
8.3.4,
8.3.5,
8.3.6.4,
9.2.1.2,
9.2.5.1,
9.3.1,
9.3.2.1,
9.4.2.1;
Tables
3.1,
4.1;
Figure 3.3
C57BL/10 (B10)
1.1.2,
1.2.2,
3.4.2;
Tables
3.1,
4.1
C57L
6.2.3
C58
6.2.3
CAST/Ei
3.2.5,
9.4.2.1,
9.4.2.2,
Table 3.1;
Figure 3.3
CBA
1.2.2,
4.1;
Table 4.1
DBA
1.2.2,
3.1,
3.4.2,
4.1,
6.2.3,
8.2.3,
8.3.4,
8.3.6.4,
9.4.2.1;
Tables
3.1,
4.1
FVB/N
4.1,
6.2.2.2;
Tables
3.1,
4.1
LP/J
8.3.6.4
LT/Sv
9.1.2.3
MOLF/Ei
3.1,
3.2.5,
9.4.2.1
SJL
4.1,
6.2.3,
8.2.3,
Table 4.1
SPRET/Ei
3.2.5;
Table 3.1;
Figure 3.3
strain, choice of
6.2.5.1
strain distribution pattern
9.2.2.1,
9.2.2.4,
9.2.3,
9.3.2.2;
Figure 9.6;
Appendix E: Glossary of Terms
stud male
4.5.1
fertile
6.2.4
sterile
6.2.5.1,
6.2.5.2;
Figure 6.1
Sturtevant, A.H.
7.2.1
substrains
3.1,
3.4.2
superovulation
4.1,
6.2.3;
Table 4.1
susceptibility loci
9.2.5.1,
9.2.5.2
swept radius
9.2.2.2,
9.2.2.3,
9.4.4.2,
9.5.4.2;
Figures
9.13,
9.14
Switzerland
5.2.2.1
synapsis
5.2.3.1,
10.1.2
synteny, conservation of
10.2.1,
Appendix E: Glossary of Terms
systematics
Mus species group
2.3.1,
2.3.2,
2.3.3
rodent
2.1;
Table 2.1
t complex
Figure 6.1
t haplotype
2.3.3
t-test
Appendix D2
Taconic Farms
3.1;
Table 3.1;
Appendix A
tandem repeat elements
5.3.3.3,
5.3.4
TaqI
8.2.2,
9.4.2.1
targeted mutagenesis
3.4.4,
5.5.1,
6.4,
7.4.1,
Appendix E: Glossary of Terms
repository of mutants
6.5.2
strain selection
6.2.2.2,
6.2.3,
6.2.4,
6.2.5
targeting vector
6.4.2
Taylor, Benjamin
7.2.4.2
telomeres
5.3.1.1,
7.2.3.1,
10.2.2.2
teratomas
ovarian
9.1.2.3
testicular
6.4.5
testis
4.2.1
tobacco mouse
5.2.2.1
transcripts, number of
5.1.5.2
transgenics
6.3,
7.4.1,
Appendix A,
Appendix E: Glossary of Terms
animals
4.3.3
beta-globin
5.3.3.2
coisogenic
6.2.2.1
database
6.5.2
history
6.3.1
homozygote detection
6.3.2
mapping
10.2.2.2
nomenclature
3.4.5
strain selection
6.2.2.2,
6.2.3,
6.2.4,
6.2.5
tracking transgene
6.3.2
YAC transgenes
6.5.3
translocation
8.1,
8.3.1.1,
10.2.2.2;
Figure 8.7;
Appendix E: Glossary of Terms
genetic markers
5.2.2.2
heterozygotes
5.5.1,
7.3.5
radiation-induced
6.1.2
reciprocal
5.2.3;
Figure 5.3
Robertsonian
5.2.2,
8.4.2,
9.1.2.2,
Appendix E: Glossary of Terms
transplantation
nuclear
5.5.1,
6.2.1
ovary
4.5.2
tissue
3.3.3.1
transposition
5.3.2.2,
5.3.3.1
trisomies, partial
5.2.3.3
tumor suppressor genes
10.1.2
two-dimensional gel electrophoresis
DNA
8.2.4;
Figure 8.5
proteins
7.3.4
unequal crossing over
5.2.3.1,
5.3.2.3,
5.3.3.1,
5.3.3.3,
5.4.4,
5.4.5,
8.2.1,
8.2.3,
8.3.6.1;
Figures
5.6,
8.4;
Appendix E: Glossary of Terms
3'-untranslated regions
8.3.1.2
urine
4.3.1
vagina, closed
4.4.1
vaginal plug
1.3.2,
4.3.5,
4.5.1,
6.2.4
variance, determination
Appendix D2
vasectomy
6.2.5.2
viral infection, germ line
6.3.1
VL30 elements
5.4.1,
8.2.4
VNTR, see
minisatellites
voles
2.3.1;
Table 2.1
walking, chromosomal
10.3.3.2,
10.3.3.3,
Figure 10.1,
Appendix E: Glossary of Terms
weaning
4.4.5
weight
4.4.7
Whitehead Institute Genome Center
8.3.6.5,
9.4.4.4,
Appendix B1.1
whole genome linkage map
2.3.5,
7.2.4.3,
9.1,
9.5.4.2
Wilson, Alan
2.3.2
Windows
AppendixB1.1
World Wide Web
AppendixB1.1
wormy mice
2.3.3
X chromosome inactivation
5.5.2
yeast artifical chromosomes
1.3.4,
6.5.3,
7.1.4,
8.3.6.5,
10.3.3,
10.3.4,
Appendix E: Glossary of Terms
zoo blots
10.3.4.5